New acute leukaemia

Recommended for all patients

1. Bone marrow aspirate (morphology)
2. Flow cytometry

Desirable for all patients

1. Bone marrow biopsy (trephine)

If available

1. Karyotype
2. FISH for t(8;21), t(9;22), inv(16), t(15:17)
3. Molecular: FLT3, NPM1

Additional

1. Next generation sequencing for myeloid gene panel